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Mulan performs local multiple DNA sequence alignments of finished and draft-quality sequences. It identifies transcription factor binding sites evolutionarily conserved across multiple species. Abstract Instructions Example (GATA3 locus)

NUMBER OF SPECIES: (Including the reference sequence)

ALL FINISHED SEQUENCES :: TBA alignment DRAFT SECONDARY SEQUENCES :: refine alignment Finished (one contig per sequence) DNA sequences. All the sequences can have gene annotation and any of the sequences can be represented as a base sequence. Identification of transcription factor binding sites conserved across multiple species could be performed with the use of interconnected tool. Draft (multiple contigs per sequence) DNA sequences with a finished reference sequence. Reference sequence can not be changed and genes can not be annotated for the secondary sequences. Order-and-orient maps based on the reference sequence will be constructed for each of the secondary sequences.

Select to increase alignments sensitivity (useful for diverged sequences)

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NCBI DCODE.org Comparative Genomics Developments